Arginase Inhibition Ameliorates Hepatic Metabolic Abnormalities in Obese Mice
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منابع مشابه
Arginase Inhibition Ameliorates Hepatic Metabolic Abnormalities in Obese Mice
OBJECTIVES We examined whether arginase inhibition influences hepatic metabolic pathways and whole body adiposity in diet-induced obesity. METHODS AND RESULTS After obesity induction by a high fat diet (HFD), mice were fed either the HFD or the HFD with an arginase inhibitor, Nω-hydroxy-nor-L-arginine (nor-NOHA). Nor-NOHA significantly prevented HFD-induced increases in body, liver, and visce...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0103048